Thiohydantoins, which are the sulfur analogues of hydantoins, are the privileged scaffolds in modern synthetic organic chemistry due to their important pharmacological properties and their usage as pesticides, reagents for dyes, C-terminal protein sequencing and metal-cation complexation agents. 
In this project, the atroposelectivity observed in the synthesis of the axially chiral 2-thiohydantoin derivatives and the role of the solvent on the product distribution is rationalized with computational tools. This project is carried out in collaboration with Prof. I. Dogan (BU).
 Z.P. Haslak, S.A. Cinar, S. S. Ozbek, G. Monard, I. Dogan and V. Aviyente Org. Biomol. Chem., 2020, 18, 2233-2241.